Do I still need NIPT after PGT-A?
This deserves a careful answer, because it is easy to assume PGT-A has already covered it. PGT-A tests a small number of cells taken from the outer layer of the embryo โ the part that becomes the placenta โ before transfer. It reduces the chance of transferring an embryo with a chromosome abnormality. It does not guarantee a chromosomally normal baby. Both PGT-A and NIPT have the same underlying limitation: both analyse placental-lineage cells rather than the baby, and both can therefore be misled by mosaicism where the placenta and baby differ. So they are not simply duplicates, but neither is diagnostic. What to discuss with your obstetrician and fertility specialist together: Whether NIPT adds useful information in your specific case, given what PGT-A showed. That neither test excludes single gene conditions, neural tube defects or structural abnormalities. That your anomaly scan remains important regardless. That if either raises a concern, only CVS or amniocentesis gives a definitive answer. There is a practical point too โ an embryo reported as euploid can still result in an affected pregnancy, uncommonly, and a normal NIPT after PGT-A adds a layer of reassurance some parents value even where the additional information is limited. Your fertility clinic and obstetrician should agree an approach between them rather than leaving you to reconcile two separate recommendations.
Review by Fertility Connect Medical Team Pending
This information is general and does not replace advice from your own clinician.